The department of Nuclear Medicine was started in 1982 as part of the 'Nuclear Technique Centre' of Andhra University in the ground floor of the pediatrics block (old cardiology block) with a thyroid probe.

A full pledged department was set up in 1984 with Dr S. Narasimha Rao as in-charge. He was made the Professor in 1987. The department was equipped with a medical fast scanners and RA counter.

The present building opposite Rajendra Prasad ward was inaugurated  on 8.10.1993. Subsequently the department procured a gamma camera in 1993. The department provides diagnostic services for thyroid brain, ear, kidney, bone and blood vessel disease and also cancer.